Format
Sealed research vial
Trust signal
COA-backed inventory
99%+ Purity
Lab-grade supply. Limited AU stock.
A$229
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Fast AU dispatch, tracked delivery, and documentation-ready inventory.
Why labs buy from APL
High purity, consistent supply, and fast AU-wide dispatch.
Certificate of Analysis
COA library
Browse the current COA library and available product documentation.
SS-31 is a tetrapeptide Szeto-Schiller compound (D-Arg-2′6′-dimethylTyr-Lys-Phe-NH₂) that selectively partitions to the inner mitochondrial membrane by binding cardiolipin.
Research applications centre on mitochondrial bioenergetics and cardiolipin biology. SS-31 is frequently used as a positive control in mitochondrial ROS assays, cristae remodelling studies, and ATP synthesis efficiency experiments. Its protease-resistant design makes it suitable for primary cell cultures where longer peptide incubation times are needed.
Browse Inventory
In research literature, SS-31 is generally treated as a tetrapeptide Szeto-Schiller compound (D-Arg-2′6′-dimethylTyr-Lys-Phe-NH₂) that selectively partitions to the inner mitochondrial membrane by binding cardiolipin. SS-31 (elamipretide) carries a net 3+ charge at physiological pH that drives electrophoretic accumulation at the negatively charged inner mitochondrial membrane (IMM). There it interacts with cardiolipin — an anionic phospholipid unique to the IMM and essential for cristae architecture and respiratory complex assembly. Cardiolipin-SS-31 binding has been studied for: stabilising cytochrome c interaction with Complex IV, improving electron transfer efficiency at Complex I and III, and reducing superoxide/H₂O₂ generation during oxidative stress conditions. The non-natural D-Arg and 2′6′-dimethylTyr residues confer protease resistance, enabling extended incubation in cell-based assay formats.
Research applications centre on mitochondrial bioenergetics and cardiolipin biology. SS-31 is frequently used as a positive control in mitochondrial ROS assays, cristae remodelling studies, and ATP synthesis efficiency experiments. Its protease-resistant design makes it suitable for primary cell cultures where longer peptide incubation times are needed. For laboratory teams, the practical emphasis is usually on sequence identity, receptor or pathway relevance where documented, and whether SS-31 behaves consistently across stability, purity, and analytical verification workflows. Variant labels on this page support clearer internal referencing when multiple labelled variants are under review.
Potential research applications for SS-31 should be framed strictly in analytical and laboratory terms. Typical reasons a team might review this product page include:
Handling decisions should always follow the vial label, internal SOPs, and any product-specific documentation. A conservative laboratory baseline for SS-31 is:
If a product-specific file is not attached to this listing, the wider COA library remains the correct reference point for current published documentation. The COA section is useful for confirming how the product is labelled in the catalogue, whether purity information has been published, and whether the laboratory record for the material is complete before bench use.
When teams compare SS-31 with NAD+, PT-141, and Glow, COA access also helps keep comparator decisions grounded in documented material identity rather than assumption. That is especially important for research pages that combine pricing, variant selection, and analytical records on a single URL.
Certificate of Analysis
COA library
Browse the current COA library and available product documentation.
It brings together 3 labelled variants: 10mg, 25mg, and 50mg, current pricing context, stock visibility, COA access, and internal links to related catalogue pages so a laboratory buyer can review the material from a single reference URL.
SS-31 is generally discussed as a tetrapeptide Szeto-Schiller compound (D-Arg-2′6′-dimethylTyr-Lys-Phe-NH₂) that selectively partitions to the inner mitochondrial membrane by binding cardiolipin. The most relevant background is sequence behaviour, pathway or receptor context where documented, and analytical consistency under controlled laboratory conditions.
Use the label, COA, and internal SOPs as the primary guide. In general, store the material under controlled laboratory conditions, minimise avoidable environmental exposure, and keep variant tracking records current.
This page links the broader COA library when a product-specific document is not attached. Laboratories should use the published documentation set that is currently available for the listing.
No. The page should be interpreted strictly in a research and laboratory context. It does not provide dosage guidance, treatment claims, or human or animal use instructions.
